International Speaker Seminar Series

The International Speaker Seminar Series (ISSS) and group discussions are free and OPEN TO ALL.

Seminars are broadcasted free of charge to any Canadian research centre interested in participating by videoconference. Videoconferencing fees are covered, but not long distance charges.

Unless otherwise indicated, all seminars and group discussions will be held from 12:00 p.m. to 2:00 p.m. EST on the first Friday of every month. The table below will be updated with the location of each upcoming seminar, as follows:

DateTimeLocationsMap & Directions
June 1, 2017Seminar 1:
9:00am to 10:00am
Peter Gilgan Centre for Research and Learning
Main Auditorium, 2nd Floor
686 Bay Street, Toronto
June 2, 2017Seminar 2:
12:00pm to 1:00pm
The Hospital for Sick Children
Daniels Hollywood Theatre, Room 1246, First Floor, Black Wing
555 University Avenue, Toronto
June 2, 2017Post-Seminar Group Discussion:
1:00pm to 2:00pm
The Hospital for Sick Children
The Rotunda, First Floor, Black Wing
555 University Avenue, Toronto

With this series, and in the context of genetic epidemiology and statistical genetics research, CIHR STAGE aims to:

  • expose trainees to high-calibre international research
  • further interdisciplinary research innovation, discovery, and learning
  • foster a cohesive research community of genetic epidemiologists and statistical geneticists in Canada
  • promote rigorous and relevant research in this field
  • enable new networks of collaborative research

September 2016 – June 2017

DateTimeGuest SpeakersTalk TitleHost
September 30, 201612:00pm to 1:00pmdsc_0332-cropDr. Peter Kraft
Professor of Epidemiology and Biostatistics,
Director of Program in Genetic Epidemiology and Statistical Genetics,
Harvard T.H. Chan School of Public Health
Recent advances in the integrative molecular epidemiology of breast cancer.

Abstract: click here
Sponsored by OICR
November 4, 201612:00pm to 1:00pmMatthew Freedman, M.D.Dr. Matthew Freedman
Associate Professor, Harvard Medical School;
Associate Physician, Dana-Farber Cancer Institute;
Associate Member, Broad Institute
The Genomics and Epigenomics of Prostate Cancer

Sponsored by McLaughlin Centre
December 2, 201612:00pm to 1:00pmDr. Jeff Leek
Associate Professor of Biostatistics, Johns Hopkins Bloomberg School of Public Health;
Co-Director of the Johns Hopkins University Data Science Lab
Computational re-annotation of the human transcriptome with the recount project

Sponsored by Lunenfeld-Tanenbaum Research Institute
February 3, 201712:00pm to 1:00pmDr. Goncalo Abecasis
Felix E. Moore Collegiate Professor and Department Chair, Department of Biostatistics, University of Michigan School of Public Health
Sequencing and Analysis of 10,000s of Human Genomes: Challenges and Opportunities

Sponsored by Lunenfeld-Tanenbaum Research Institute
March 3, 201712:00pm to 1:00pmDr. Joanna Biernacka
Director of Psychiatric Genomics and Pharmacogenomics Program, Professor of Biostatistics, Mayo Clinic College of Medicine and Science
Psychiatric Genomics and Pharmacogenomics: Recent Advances and Ongoing Challenges

Sponsored by CAMH
April 7, 201712:00pm to 1:00pmDr. Elizabeth Hauser
Duke Molecular Physiology Institute (DMPI),
Department of Biostatistics and Bioinformatics,
Department of Medicine,
Duke University School of Medicine
Gene-Environment Interactions in Cardiovascular Disease: Air Pollution and Stress

Sponsored by Lunenfeld-Tanenbaum Research Institute
May 5, 201712:00pm to 1:00pmDr. Ellen L. Goode
Department of Health Sciences Research
College of Medicine, Mayo Clinic
Integrative Molecular Epidemiology of Ovarian Cancer

Sponsored by OICR
June 1, 20179:00am to 10:00amDr. Neil Risch
Professor, Epidemiology and Biostatistics
Director, Institute for Human Genetics
University of California, San Francisco
Genetic Epidemiology Research Based in Electronic Health Records, Part 1. Population Structure, Mating Patterns and Self-Identified Race/Ethnicity

Sponsored by Genetic and Genome Biology, Sick Kids
June 2, 201712:00pm to 1:00pmDr. Neil Risch
Professor, Epidemiology and Biostatistics
Director, Institute for Human Genetics
University of California, San Francisco
Genetic Epidemiology Research Based in Electronic Health Records, Part 2. Linking the genome to longitudinal disease and trait data

Sponsored by Genetic and Genome Biology, Sick Kids

February 2016 – June 2016

DateTimeGuest SpeakersTalk TitleHost
February 5, 2016noon to 1:00pmG PARE_photoDr. Guillaume Paré
Director, Genetic and Molecular Epidemiology Laboratory, Hamilton Health Sciences
Associate Professor, Department of Pathology and Molecular Medicine, McMaster University
A Method to Estimate the Contribution
of Regional Genetic Associations
to Complex Traits from Summary
Association Statistics
France Gagnon

This is a partnered seminar with the
Centre for Genetic Medicine,
The Hospital for Sick Children
March 4, 2016noon to 1:00pmdesk2b_bfvDr. Benjamin Voight
Assistant Professor, Department of Systems Pharmacology and Translational Therapeutics,
Department of Genetics, University of Pennsylvania, Perelman School of Medicine
Genome-wide mutation rates viewed through a seven-nucleotide windowAnna Goldenberg

This is a partnered seminar with The McLaughlin Centre, University of Toronto
April 1, 2016CANCELED
Will be rescheduled for a later date.
E Goode_croppedDr. Ellen L. Goode
Professor of Epidemiology, Health Sciences Research, Mayo Clinic
Molecular epidemiology of ovarian cancerJennifer Brooks

This is a partnered seminar with the Ontario Institute for Cancer Research.
May 6, 20162016 Biostatistics Research Day
June 3, 2016noon to 1:00pmShili-LinDr. Shili Lin
Professor of Statistics, Department of Statistics, Ohio State University
Addressing the Correlated Feature in Sequencing-Based DNA Methylation
Data for Detection of Differentially Methylated Regions
Shelley Bull

This is a partnered seminar with the Lunenfeld-Tanenbaum Research Institute

October 2014 – June 2015

DateTimeGuest SpeakersTalk TitleHost
Oct. 3, 2014noon to 1:00 pmDr. Paul Brennan
Section and Group Head, Genetic Epidemiology Group, International Agency for Research on Cancer, World Health Organization
What proportion of oropharynx cancers are caused by HPV, and can we use HPV antibodies to identify them early?Rayjean Hung
Nov. 7, 2014noon to 1:00 pmDr. Richard Simon
Chief, Biometric Research Branch, Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health
Development of Predictive Classifiers Based on High Dimensional Data
Validation for an Intended Use
Shelley Bull
Dec. 5, 2014noon to 1:00 pmDr. John Stamatoyannopoulos
Associate Professor, Department of Genome Sciences, University of Washington
Decoding the human genome: Reading nature’s text, punctuation, and ongoing editsMichael Wilson
POSTPONEDnoon to 1:00 pmJoan E. Bailey-Wilson
Co-Chief & Senior Investigator, Inherited Disease Research Branch, National Human Genome Research Institute, National Institutes of Health
Mar. 6, 2015noon to 1:00 pmTBCTBCTBC
Apr. 10, 2015noon to 1:00 pmRafael Irizarry, Professor, Department of Biostatistics, Harvard School of Public Health
Professor, Biostatistics and Computational Biology, Dana Dana-Farber Cancer Institute

Rafael Irizarry's lab page.
May 1, 2015noon to 1:00 pmCurtis Huttenhower, Associate Professor of Computational Biology and Bioinformatics
Department of Biostatistics
Harvard School of Public Health
Jun. 5, 2015noon to 1:00 pmTBCTBCTBC

October 2013 – June 2014

DateTimeGuest SpeakersTalk TitleHost
Oct. 4, 2013noon to 1:00 pmProf. Andreas Ziegler
Professor and head of the Institute of Medical Biometry and Statistics, University Medical Center Schleswig-Holstein, Campus Luebeck,
University of Luebeck, Germany
Probability Machines: Estimating individual probabilities using machine learning methodsFrance Gagnon
Nov. 1, 2013noon to 1:00 pmDr. Bruce Rannala
Professor, Department of Evolution and Ecology, College of Biological Sciences, UC Davis Genome Center
Statistical analysis of pooled samples for whole-genome case-control associations: A SNP GWAS of lung cancer susceptibility genes in the Northern Thai populationFrance Gagnon
Dec. 6, 2013noon to 1:00 pmRescheduled for April 4, 2014.
Jan. 31, 20141:00 to 2:00 pmDr. Erwin Schurr
Investigator, Centre for the Study of Host Resistance

Professor, Department of Human Genetics

Professor, Department of Medicine, Division of Experimental Medicine
McGill University
Genetic dissection of complex infection phenotypesFrance Gagnon
Mar. 7, 2014noon to 1:00 pmDr. Chris Amos
Associate Cancer Center Director for Population Sciences
Head, Center for Genomic Medicine
Professor, Department of Community and Family Medicine
Geisel School of Medicine, Dartmouth College
Genetic Architecture of Lung Cancer SusceptibilityRayjean Hung
Apr. 4, 2014noon to 1:00 pmDr. Bhramar Mukherjee
Associate Professor, University of Michigan School of Public Health
Gene-environment interactions: new directions and novel applicationsHoward Hu
May 2, 2014noon to 1:00 pmDr. Frank Dudbridge
Professor, Department of Non-communicable Disease Epidemiology and Faculty of Epidemiology and Population Health
London School of Hygiene & Tropical Medicine
Explaining heritability and predicting risk with polygenic scoresShelley Bull
Jun. 6, 2014noon to 1:00 pmDr. Xihong Lin
Professor, Department of Biostatistics
Harvard School of Public Health
Statistical Genetics and Genomics in the Big Data Era: Opportunities and Challenges in Research and TrainingTBC

October 2012 – May 2013

DateTimeGuest SpeakersTalk TitleHost
Sep. 14, 2012noon to 1:00 pmDr. Marjo-Ritta Jarvelin
Divisional Director of Postgraduate Studies
Professor and Chair, Department of Epidemiology and Biostatistics, School of Public Health, MRC-HPA Centre for Environment and Health, Faculty of Medicine
Imperial College London
Genetics of Early Growth

ISSS Colour Poster [ PDF ]
Lyle Palmer
Oct. 5, 2012noon to 1:00 pmDr. Sharon Browning
Associate Professor, Department of Biostatistics
University of Washington
Identity by descent in
“unrelated” individuals

ISSS Colour Poster [PDF]
Lei Sun
Nov. 2, 2012noon to 1:00 pmDr. Duncan C. Thomas
Professor and Director, Biostatistics Division
Verna R. Richter Chair in Cancer Research, Department of Preventive Medicine
University of Southern California
Two-phase family-based designs for next generation sequencingShelley B. Bull
Dec. 7, 2012noon to 1:00 pmDr. Howard Hu
Director and Dean
Dalla Lana School of Public Health
University of Toronto
Looking behind the curtain: Lead Toxicity as a Case Study of Methodologic Challenges in Gene-Environment Interactions ResearchFrance Gagnon
Jan. 11, 2013noon to 1:00 pmDr. David Tregouet
Head director, Institute for Cardio-Metabolism and Nutrition (ICAN), Genomics Department, Pierre and Marie Curie University Campus
Research Director, 2nd Class, Mixed Research Unit S 937 - Genomics of Venous Thrombosis, Institut national de la santé et de la recherche médicale (INSERM)
Haplotypes & Imputation, Two Complementary Tools: A Case Study on GenomeWide Expression StudiesFrance Gagnon
Jan. 25, 20131:00 to 2:00 pmDr. Florence Demenais
Director, Director of Research, Institut National de la Recherche Médicale (INSERM)
Head of the Genetic Variation and Human Diseases Unit, INSERM-University Paris
Common and rare variants in the genetic susceptibility to melanoma

ISSS Colour Poster [PDF]
Shelley B. Bull
Mar. 1, 2013noon to 1:00 pmKimberly D. Siegmund
Associate Professor of Biostatistics
Department of Preventive Medicine, USC Keck School of Medicine
University of Southern California
DNA Methylation Studies using Illumina HumanMethylation450 BeadArrays

ISSS Colour Poster [PDF]
Shelley B. Bull
Apr. 5, 2013noon to 1:00 pmDr. Mathieu Lupien
Scientist, Ontario Cancer Institute
OICR Investigator, Ontario Institute for Cancer Research (OICR)
Assistant Professor, Department of Medical Biophysics, University of Toronto
Epigenomics reveal the function of genetic risk-variants in cancer

ISSS Colour Poster [PDF]
Michael Wilson (TBC)
May 3, 2013noon to 1:00 pmDr. George Davey-Smith
Scientific Director of The Avon Longitudinal Study of Parents and Children (ALSPAC) & MRC Centre for Causal Analyses in Translational Epidemiology
Professor of Clinical Epidemiology, School of Social and Community Medicine
University of Bristol
How Can Genetic Epidemiology Help Identify Modifiable Causes of Disease

ISSS Colour Poster [PDF]
Lyle Palmer

October 2011 – June 2012

DateTimeGuest SpeakersTalk TitleHost
October 7, 2011noon to 1:00 pmDr. Stephen S. Rich
Director, Center for Public Health Genomics
Harrison Professor & Vice Chair, Department of Public Health Sciences, University of Virginia
The Search for Genes Associated with Ischemic Stroke through GWAS and Exome Sequencing

ISSS Colour Poster [ PDF ]
Andrew Paterson
November 4, 2011
December 2, 2011noon to 1:00 pmDr. Ellen M. Wijsman
Professor, Division of Medical Genetics and Department of Biostatistics
University of Washington
New genomics technologies and complex traits: what do we gain, and what are the challenges?

ISSS Colour Poster [ PDF ]
France Gagnon
January 6, 2012noon to 1:00 pmDr. Suzanne M. Leal
Director, Center for Statistical Genetics
Department of Molecular and Human Genetics
Baylor College of Medicine
From Linkage Studies to Next Generation Sequencing and Back Again: Leveraging Next Generation Sequence Data and Families to Identify Disease Genes

ISSS Colour Poster [ PDF ]
January 27, 20121:00 to 2:00 pmDr. Clarice R. Weinberg
Chief, Biostatistics Branch, National Institute for Environmental Health Sciences, National Institutes of Health
Using nuclear families to find genes related to conditions with onset early in life.

ISSS Colour Poster [ PDF ]
Andrew Paterson
March 2, 2012noon to 1:00 pmDr. John Witte
Professor of Epidemiology & Biostatistics and Urology
University of California, San Francisco
Associate Director
Institute for Human Genetics
Head, Division of Cancer Epidemiology
Co-Leader, Program in Cancer Genetics, Helen Diller Family Comprehensive Cancer Center
Design and Analysis of Next-generation Genetic Epidemiological Studies.

ISSS Colour Poster [ PDF ]
Rayjean Hung
April 13, 2012noon to 1:00 pmDr. Veronica J. Vieland
Vice President for Computational Research and Director
Battelle Center for Mathematical Medicine at The Research Institute at Nationwide Children’s Hospital

Professor, Department of Pediatrics and Department of Statistics
The Ohio State University College of Medicine
Calibration of Statistical Evidence using Principles of ThermodynamicsLisa Strug
May 4, 2012noon to 1:00 pmDr. Alice S. Whittemore
Professor of Epidemiology and Biostatistics
Department of Health Research and Policy
Stanford University School of Medicine
Evaluating Personal Risk ModelsLaurent Briollais

May 2010 – October 2011

DateTimeGuest SpeakersTalk TitleHost
October 5, 20103:30 to 4:30 pmDr. Martin D. Tobin
Professor of Genetic Epidemiology and Public Health
MRC Clinician Scientist Fellow
Genetic Epidemiology Group
Departments of Health Sciences & Genetics
University of Leicester
Copy Number Variation and Complex Human Disease: Examples of Two Recent Studies

ISSS Colour Poster
[ PDF (1.5 MB) ]
Lyle Palmer
November 19, 2010noon to 1:00 pmDr. Thomas J. Hudson
President and Scientific Director
Ontario Institute for Cancer Research
Genome Variation and Cancer

ISSS Colour Poster
[ PDF (556 KB) ]
France Gagnon
December 3, 2010noon to 1:00 pmDr. Sündüz Keles
Associate Professor
Departments of Statistics and Biostatistics & Medical Informatics
University of Wisconsin School of Medicine and Public Health
Multi-reads enable detection of novel peaks in ChIP-seq analysis

ISSS Colour Poster
[ PDF (1 MB) ]
Lei Sun
January 14, 2011noon to 1:00 pmProf. Michael Boehnke
Richard G. Cornell Distinguished University Professor of Biostatistics,
School of Public Health
, University of Michigan

Director, Center for Statistical Genetics, and Genome Science Training Program
Identifying Genes for Type 2 Diabetes and Related Traits by Genome-Wide
Association and Sequencing Studies
Shelley B. Bull
February 4, 2011noon to 1:00 pmProf. Colin B. Begg
Chair, Department of Epidemiology and Biostatistics
Memorial Sloan-Kettering Cancer Centre
Distinguishing Second Primary Cancers From Metastases: Statistical Challenges in Testing Clonal Relatedness of Tumors

ISSS Colour Poster [ PDF (600 KB) ]
Laurent Briiollais
March 4, 2011noon to 1:00 pmProf. Pierre-Emmanuel Morange
INSERM, UMR S 626, Université de la Méditerranée, Marseille, France
Lessons from Genome-Wide Association Studies in Venous Thrombosis

ISSS Colour Poster
[ PDF (500 KB) ]
France Gagnon
April 1, 2011noon to 1:00 pmProf. Chiara Sabatti
Associate Professor, Department of Health Research and Policy (Biostatistics) and
Statistics (by Courtesy)
Stanford University
Genetics in a Finnish Birth Cohort

ISSS Colour Poster
[ PDF (971 KB) ]
Lei Sun
May 6, 2011noon to 1:00 pmProf. Terri H. Beaty
Professor and Deputy Chair, Department of Epidemiology in the Bloomberg School of Public Health
Johns Hopkins University
Impact of Study Design in Genome Wide Association Studies

ISSS Colour Poster
[ PDF (532 KB) ]
John McLaughlin


Seminars are sponsored by The Hospital for Sick Children (Genetics & Genome Biology Program), the Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, the Ontario Institute for Cancer Research, the Department of Statistics of the University of Toronto, the Ontario Cancer Institute of the University Health Network, and the CIHR Institute of Genetics.